Saturday, July 5th 2008 7:58PM EDT

SynthoGraft™: The Next Generation of Regeneration

Particle Size	Volume	Vials	Part Number
50-500μm	0.5g	5	260-400-150
50-500μm	1.0g	5	260-400-151
50-500μm	2.0g	5	260-400-152
500-1000μm	0.5g	5	260-400-500
500-1000μm	1.0g	5	260-400-501
500-1000μm	2.0g	5	260-400-502

SynthoGraft™ Considerations

Indications and Usage:
• SynthoGraft™ is designed for the filling and/or reconstruction of either traumatic or degenerative multi-wall bone defects, augmentation of the sinus floor, augmentation of atrophied alveolar ridges, filling of periodontal or other alveolar bone defects, tooth sockets and osteotomies as well as the preservation of the alveolus for the preparation of an implant site.

Warnings:
• SynthoGraft™ should be used only by or under the supervision of trained personnel with experience in the surgical techniques associated with biomaterials.
• SynthoGraft™ is packaged and sterilized for single use only.
• Do not apply SynthoGraft™ dry.
• Do not saturate SynthoGraft™ with any solution (e.g. physiological saline, NaCl or antibiotics) other than the patient’s blood.
• Do not mix SynthoGraft™ with any other bone grafting material.
• Do not resterilize SynthoGraft™.
• Discard any unused SynthoGraft™ granulate.
• Not intended for immediate loading.
• Do not overfill defect site.
• Secure SynthoGraft™ to prevent migration of materials.
• Do not use if package has been opened, damaged or if the expiration dated has passed.
• Do not compromise blood supply to the defect area.

SynthoGraft's unique design provides for an optimal environment for bone regeneration. With both micro-porosity and nano-porosity, SynthoGraft has a greater surface area compared to other synthetic bone grafting materials — allowing for ideal bone regeneration. As a pure synthetic material, SynthoGraft does not have the inherent risks associated with biologically-derived bone graft materials.